Delirium tremens typically appears within what time frame after the last drink?

• A. 24-48 hours after last drink
• B. 48-96 hours after last drink
• C. 1-2 weeks after last drink
• D. Immediately after cessation

Answer: (B)

Delirium tremens is a late and severe manifestation of alcohol withdrawal, arising after the brain has adapted to daily alcohol exposure and suddenly loses that input. The neurochemical changes take time to escalate to delirium, so it typically surfaces a few days after the last drink. The most common window is about two to four days post-cessation, often described as 48–96 hours. This timing fits the pattern of progression from early withdrawal symptoms to the delirious state, which is why this range is the best match.

Understand that delirium tremens is a medical emergency, with symptoms like severe confusion, tremors, agitation, autonomic instability, and possible hallucinations, requiring prompt treatment. Earlier onset (within 24–48 hours) can occur with milder withdrawal, while waiting more than a week is not the typical course for delirium tremens. Immediate cessation does not produce delirium tremens right away; it develops after a few days of withdrawal.